ErbB2/Her2 antibody

Catalog No. ABIN306627

This anti-ErbB2/Her2 antibody is a Sheep Polyclonal antibody detecting ErbB2/Her2 in WB. Suitable for Human.

Quick Overview for ErbB2/Her2 antibody (ABIN306627)

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Reactivity: Human

Host: Sheep

Clonality: Polyclonal

Conjugate: This ErbB2/Her2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-ErbB2/Her2 Antibody

Isotype: IgG

Application Details

Application Notes: Antibody can be used for Western blotting (5-10 ug/ml). Positive Control: Breast carcinomas.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/ml

Storage: -20 °C

Target Details for ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Alternative Name: c-ErbB-2

Background: C-erbB-2 is a receptor tyrosine kinase. It exhibits extracellular domains with two cysteine-rich sequences, and a cytoplasmic tyrosine kinase domain flanked by large hydrophilic tails that carry several tyrosine autophosphorylation sites. Approximately 25% of primary breast and ovarian tumors were found to overexpress the protein. Synonyms: HER2, neu, p185erbB2, MLN 19, CD340.

UniProt: P04626

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development